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Flea & Tick Control
Frontline Plus

Frontline Plus Flea & Tick Topical Treatment for Cats & Kittens

Our Rating
★★★★★ 3.5

Frontline Plus for Cats | Kills Fleas, Eggs, Larvae & Ticks, No Prescription Needed

Quick Facts:

  • Best for: Cats and kittens 8 weeks and older, 1.5+ lbs
  • Main active ingredients: Fipronil & (S)-methoprene
  • Format: Topical monthly applicator, 6- or 8-dose packs
  • Key support: Kills fleas, flea eggs, flea larvae, chewing lice & ticks
  • Prescription status: Not required — available over-the-counter
  • Ideal for: Cats needing a single-application monthly treatment, including breeding/pregnant/lactating cats

Description: Frontline Plus for Cats uses the same fipronil and (S)-methoprene combination as the dog formula, adapted specifically for feline dosing, and is approved for cats and kittens as young as 8 weeks old weighing 1.5 lbs or more. The single active-ingredient combination works in two complementary ways: fipronil kills adult fleas, ticks, and chewing lice on contact, while (S)-methoprene disrupts the development of flea eggs and larvae, preventing a household infestation from re-establishing itself even after visible fleas are gone. One topical application, applied to a single point on the cat's skin, provides a full 30 days of protection and remains effective even if the cat is bathed or gets caught in the rain. Notably, Frontline Plus for Cats is approved for use in breeding, pregnant, and lactating queens, a detail that matters for households managing a cat that's expecting or nursing kittens. Temporary irritation at the application site is possible but uncommon, and the product label recommends consulting a veterinarian if any signs persist beyond a few days. It's sold over-the-counter without a prescription, making it accessible for routine monthly flea and tick prevention without a vet visit.

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